| 20 | Mike Adams | 30 | DB | 16 | 16 | 195 | 5-10 | Delaware | 3/24/1981 | 7 | 8 | |
| 58 | Marcus Benard | 26 | | 4 | 0 | 256 | 6-2 | Jackson St. | 7/26/1985 | 2 | 0 | |
| 24 | Sheldon Brown | 32 | DB | 16 | 16 | 196 | 5-10 | South Carolina | 3/19/1979 | 9 | 8 | Philadelphia Eagles / 2nd / 59th pick / 2002 |
| 59 | Titus Brown | 25 | | 10 | 0 | 305 | 6-4 | Mississippi St. | 3/27/1986 | 3 | 1 | |
| 84 | Jordan Cameron | 23 | te | 8 | 2 | 254 | 6-5 | Tusculum | 8/8/1988 | Rook | 1 | Cleveland Browns / 4th / 102nd pick / 2011 |
| 33 | Thomas Clayton | 27 | | 3 | 0 | 225 | 5-11 | Kansas State | 4/26/1984 | 1 | 0 | |
| 68 | Oniel Cousins | 27 | ol | 4 | 1 | 315 | 6-4 | Texas-El Paso | 6/28/1984 | Rook | 0 | Baltimore Ravens / 3rd / 99th pick / 2008 |
| 16 | Josh Cribbs | 28 | wr | 16 | 7 | 192 | 6-1 | Kent St. | 6/9/1983 | 6 | 4 | |
| 4 | Phil Dawson | 36 | | 16 | 0 | 195 | 5-11 | Texas | 1/23/1975 | 12 | 0 | |
| 34 | James Dockery | 23 | | 12 | 0 | 185 | 6-1 | | 11/9/1988 | Rook | 1 | |
| 49 | Auston English | 24 | | 7 | 0 | 250 | 6-3 | | 3/10/1987 | Rook | 1 | |
| 99 | Scott Fujita | 32 | LB | 10 | 10 | 247 | 6-5 | California | 4/28/1979 | 9 | 5 | Kansas City Chiefs / 5th / 143rd pick / 2002 |
| 51 | Chris Gocong | 28 | LB | 16 | 16 | 260 | 6-2 | Cal Poly-San Luis Obispo | 11/16/1983 | 4 | 8 | Philadelphia Eagles / 3rd / 71st pick / 2006 |
| 77 | John Greco | 26 | | 15 | 0 | 320 | 6-5 | Toledo | 3/24/1985 | 3 | 0 | St. Louis Rams / 3rd / 65th pick / 2008 |
| 87 | Dan Gronkowski | 26 | | 2 | 0 | 255 | 6-6 | Maryland | 1/21/1985 | 2 | 0 | Detroit Lions / 7th / 255th pick / 2009 |
| 23 | Joe Haden | 22 | DB | 15 | 15 | 190 | 5-11 | Florida | 4/14/1989 | 1 | 7 | Cleveland Browns / 1st / 7th pick / 2010 |
| 27 | Eric Hagg | 22 | | 10 | 0 | 209 | 6-1 | Nebraska | 9/15/1989 | Rook | 1 | Cleveland Browns / 7th / 248th pick / 2011 |
| 31 | Montario Hardesty | 24 | rb | 10 | 4 | 225 | 6-0 | East Tennessee St. | 2/1/1987 | Rook | 2 | Cleveland Browns / 2nd / 59th pick / 2010 |
| 75 | Artis Hicks | 33 | ol | 9 | 3 | 320 | 6-4 | Memphis | 11/28/1978 | 8 | 1 | |
| 40 | Peyton Hillis | 25 | RB | 10 | 9 | 240 | 6-1 | Arkansas | 1/21/1986 | 3 | 4 | Denver Broncos / 7th / 227th pick / 2008 |
| 52 | D'Qwell Jackson | 28 | LB | 16 | 16 | 230 | 6-0 | Maryland | 9/26/1983 | 5 | 10 | Cleveland Browns / 2nd / 34th pick / 2006 |
| 54 | Benjamin Jacobs | 23 | | 5 | 0 | 243 | 6-4 | | 4/17/1988 | Rook | 0 | |
| 66 | Shawn Lauvao | 24 | RG | 16 | 16 | 301 | 6-3 | Arizona State | 10/26/1987 | 1 | 5 | Cleveland Browns / 3rd / 92nd pick / 2010 |
| 15 | Greg Little | 22 | WR | 16 | 12 | 220 | 6-3 | North Carolina | 5/30/1989 | Rook | 5 | Cleveland Browns / 2nd / 59th pick / 2011 |
| 55 | Alex Mack | 26 | C | 16 | 16 | 312 | 6-4 | California | 11/19/1985 | 2 | 5 | Cleveland Browns / 1st / 21st pick / 2009 |
| 56 | Kaluka Maiava | 24 | lb | 16 | 6 | 226 | 5-11 | USC | 3/22/1987 | 2 | 4 | Cleveland Browns / 4th / 104th pick / 2009 |
| 48 | Owen Marecic | 23 | fb | 14 | 4 | 248 | 6-1 | Stanford | 10/4/1988 | Rook | 1 | Cleveland Browns / 4th / 124th pick / 2011 |
| 11 | Mohamed Massaquoi | 25 | WR | 14 | 13 | 210 | 6-1 | Georgia | 11/24/1986 | 2 | 2 | Cleveland Browns / 2nd / 50th pick / 2009 |
| 7 | Brad Maynard | 37 | | 15 | 0 | 186 | 6-1 | Ball St. | 2/9/1974 | 14 | 0 | New York Giants / 3rd / 95th pick / 1997 |
| 12 | Colt McCoy | 24 | QB | 13 | 13 | 209 | 6-2 | Texas | 9/5/1987 | 1 | 5 | Cleveland Browns / 3rd / 85th pick / 2010 |
| 8 | Richmond McGee | 28 | | 1 | 0 | 203 | 6-4 | North Texas | 4/25/1983 | Rook | 0 | |
| 18 | Carlton Mitchell | 23 | | 11 | 0 | 212 | 6-4 | South Florida | 4/6/1988 | 1 | 0 | Cleveland Browns / 6th / 177th pick / 2010 |
| 92 | Jayme Mitchell | 27 | DL | 14 | 13 | 285 | 6-6 | Mississippi | 3/15/1984 | 5 | 7 | |
| 89 | Evan Moore | 26 | te | 16 | 4 | 232 | 6-7 | Stanford | 1/3/1985 | 2 | 3 | |
| 10 | Jordan Norwood | 25 | wr | 14 | 4 | 179 | 5-11 | Penn St. | 9/29/1986 | Rook | 2 | |
| 25 | Chris Ogbonnaya | 25 | rb | 11 | 4 | 220 | 6-0 | Texas | 5/20/1986 | 2 | 3 | St. Louis Rams / 7th / 211th pick / 2009 |
| 79 | Tony Pashos | 31 | RT | 12 | 12 | 337 | 6-6 | Illinois | 8/3/1980 | 7 | 4 | Baltimore Ravens / 5th / 173rd pick / 2003 |
| 21 | Dimitri Patterson | 28 | db | 14 | 1 | 196 | 5-11 | SE Missouri St.,Tuskegee | 6/18/1983 | 6 | 1 | |
| 69 | Scott Paxson | 28 | | 16 | 0 | 292 | 6-4 | Penn St. | 2/3/1983 | 3 | 2 | |
| 62 | Jason Pinkston | 24 | LG | 16 | 16 | 317 | 6-3 | Pittsburgh | 9/5/1987 | Rook | 5 | Cleveland Browns / 5th / 150th pick / 2011 |
| 64 | Ryan Pontbriand | 32 | | 11 | 0 | 255 | 6-2 | Rice | 10/1/1979 | 8 | 0 | Cleveland Browns / 5th / 142nd pick / 2003 |
| 80 | Brian Robiskie | 24 | wr | 6 | 2 | 207 | 6-2 | Ohio St. | 12/3/1987 | 2 | 0 | Cleveland Browns / 2nd / 36th pick / 2009 |
| 71 | Ahtyba Rubin | 25 | DL | 16 | 16 | 321 | 6-2 | Iowa St. | 7/25/1986 | 3 | 9 | Cleveland Browns / 6th / 190th pick / 2008 |
| 70 | Brian Sanford | 24 | | 5 | 0 | 280 | 6-2 | Temple | 9/12/1987 | Rook | 0 | |
| 91 | Brian Schaefering | 28 | | 16 | 0 | 286 | 6-4 | Lindenwood | 8/20/1983 | 2 | 2 | |
| 97 | Jabaal Sheard | 22 | DE | 16 | 16 | 264 | 6-3 | Pittsburgh | 5/10/1989 | Rook | 9 | Cleveland Browns / 2nd / 37th pick / 2011 |
| 21 | Buster Skrine | 22 | | 16 | 0 | 186 | 5-10 | Tennessee-Chattanooga | 4/26/1989 | Rook | 2 | Cleveland Browns / 5th / 137th pick / 2011 |
| 81 | Alex Smith | 29 | te | 14 | 4 | 258 | 6-4 | Stanford | 5/22/1982 | 6 | 2 | Tampa Bay Buccaneers / 3rd / 71st pick / 2005 |
| 35 | Armond Smith | 25 | | 3 | 0 | 194 | 5-9 | Hutchinson CC; Shorter; Union (KY) | 5/7/1986 | Rook | 0 | |
| 53 | Brian Smith | 22 | | 2 | 0 | 240 | 6-3 | | 1/8/1989 | Rook | 0 | |
| 90 | Quinton Spears | 25 | | 13 | 0 | 234 | 6-4 | Prairie View A&M | 3/4/1986 | Rook | 1 | |
| 96 | Emmanuel Stephens | 24 | dl | 11 | 3 | 255 | 6-3 | Mississippi | 2/17/1987 | Rook | 2 | |
| 98 | Phil Taylor | 23 | DL | 16 | 16 | 334 | 6-3 | Baylor | 4/7/1988 | Rook | 8 | Cleveland Browns / 1st / 21st pick / 2011 |
| 73 | Joe Thomas*+ | 27 | LT | 16 | 16 | 311 | 6-7 | Wisconsin | 12/4/1984 | 4 | 9 | Cleveland Browns / 1st / 3rd pick / 2007 |
| 67 | Kiante Tripp | 24 | | 3 | 0 | 276 | 6-6 | Georgia | 10/7/1987 | Rook | 0 | |
| 60 | Steve Vallos | 28 | | 1 | 0 | 297 | 6-3 | Wake Forest | 12/28/1983 | 3 | 0 | Seattle Seahawks / 7th / 232nd pick / 2007 |
| 41 | Raymond Ventrone | 25 | | 14 | 0 | 200 | 5-10 | Villanova | 10/22/1986 | 4 | 1 | |
| 6 | Seneca Wallace | 31 | qb | 6 | 3 | 196 | 5-11 | Iowa St. | 8/6/1980 | 6 | 2 | Seattle Seahawks / 4th / 110th pick / 2003 |
| 43 | T.J. Ward | 25 | DB | 8 | 8 | 199 | 5-10 | Oregon | 12/12/1986 | 1 | 4 | Cleveland Browns / 2nd / 38th pick / 2010 |
| 82 | Ben Watson | 31 | TE | 13 | 11 | 255 | 6-3 | Duke,Georgia | 12/18/1980 | 7 | 4 | New England Patriots / 1st / 32nd pick / 2004 |
| 44 | Eddie Williams | 24 | fb | 3 | 0 | 235 | 6-1 | Col. of Idaho | 8/22/1987 | 2 | 0 | Washington Redskins / 7th / 221st pick / 2009 |
| 28 | Usama Young | 26 | DB | 16 | 8 | 186 | 5-11 | Kent St. | 5/8/1985 | 4 | 5 | New Orleans Saints / 3rd / 66th pick / 2007 |
| 57 | Christian Yount | 23 | | 5 | 0 | 243 | 6-1 | UCLA | 7/8/1988 | Rook | 0 | |