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NFL Career Interceptions Leaders
| Rank | Player | Int | Years | Teams |
|---|---|---|---|---|
| 1. | Paul Krause+ | 81 | 1964-1979 | 2TM |
| 2. | Emlen Tunnell+ | 79 | 1948-1961 | 2TM |
| 3. | Rod Woodson+ | 71 | 1987-2003 | 4TM |
| 4. | Night Train Lane+ | 68 | 1952-1965 | 3TM |
| 5. | Ken Riley | 65 | 1969-1983 | cin |
| 6. | Darren Sharper | 63 | 1997-2010 | 3TM |
| Ronnie Lott+ | 63 | 1981-1994 | 3TM | |
| 8. | Dick LeBeau+ | 62 | 1959-1972 | det |
| Dave Brown | 62 | 1975-1989 | 3TM | |
| 10. | Ed Reed (34) | 61 | 2002-2012 | rav |
| 11. | Emmitt Thomas+ | 58 | 1966-1978 | kan |
| 12. | Everson Walls | 57 | 1981-1993 | 3TM |
| Johnny Robinson | 57 | 1960-1971 | kan | |
| Eugene Robinson | 57 | 1985-2000 | 4TM | |
| Bobby Boyd | 57 | 1960-1968 | clt | |
| Mel Blount+ | 57 | 1970-1983 | pit | |
| 17. | Pat Fischer | 56 | 1961-1977 | 2TM |
| Lem Barney+ | 56 | 1967-1977 | det | |
| 19. | Aeneas Williams | 55 | 1991-2004 | 2TM |
| Charles Woodson (36) | 55 | 1998-2012 | 2TM | |
| 21. | Darrell Green+ | 54 | 1983-2002 | was |
| Willie Brown+ | 54 | 1963-1978 | 2TM | |
| Eric Allen | 54 | 1988-2001 | 3TM | |
| 24. | Deion Sanders+ | 53 | 1989-2005 | 5TM |
| Ty Law | 53 | 1995-2009 | 4TM | |
| 26. | Champ Bailey (34) | 52 | 1999-2012 | 2TM |
| Jack Butler+ | 52 | 1951-1959 | pit | |
| Bobby Dillon | 52 | 1952-1959 | gnb | |
| Jimmy Patton | 52 | 1955-1966 | nyg | |
| Mel Renfro+ | 52 | 1964-1977 | dal | |
| Larry Wilson+ | 52 | 1960-1972 | crd | |
| 32. | Donnie Shell | 51 | 1974-1987 | pit |
| Bobby Bryant | 51 | 1968-1980 | min | |
| 34. | Don Burroughs | 50 | 1955-1964 | 2TM |
| Terrell Buckley | 50 | 1992-2005 | 6TM | |
| Deron Cherry | 50 | 1981-1991 | kan | |
| John Harris | 50 | 1978-1988 | 2TM | |
| Yale Lary+ | 50 | 1952-1964 | det | |
| Asante Samuel (31) | 50 | 2003-2012 | 3TM | |
| 40. | Jake Scott | 49 | 1970-1978 | 2TM |
| Ken Houston+ | 49 | 1967-1980 | 2TM | |
| 42. | Herb Adderley+ | 48 | 1961-1972 | 2TM |
| Dave Grayson | 48 | 1961-1970 | 2TM | |
| Richie Petitbon | 48 | 1959-1972 | 3TM | |
| Dave Waymer | 48 | 1980-1992 | 3TM | |
| Willie Wood+ | 48 | 1960-1971 | gnb | |
| 47. | Troy Vincent | 47 | 1992-2006 | 4TM |
| Lemar Parrish | 47 | 1970-1982 | 3TM | |
| Jimmy Johnson+ | 47 | 1961-1976 | sfo | |
| Ray Buchanan | 47 | 1993-2004 | 3TM |
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